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Fonte dati: ARCHIVIO
Aging is a fascinating and highly important topic because of its great social relevance and scientific complexity. One of the most important theories to explain this multifactorial process is the free radical theory. Such theory involves the damaging role of reactive oxygen species (ROS) on mitochondrial molecular components as lipids, proteins and mitochondrial DNA (mtDNA). Several studies have demonstrated an age-related accumulation of the number of deleted species of mtDNA as well as of the amount of a …