1 University of Southern Denmark, Department of Biochemistry and Molecular Biology, Campusvej 55, 5230 Odense M, Denmark; 2 The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, DK-2200 Copenhagen, Denmark … Corresponding author: Susanne Mandrup () … 0 0.2 0.4 0.6 0.8 1 1.2 … 0 0.2 0.4 0.6 0.8 1 1.2 … Log2(Veh / TNF - BRD4) α = 0.74 R = 0.81 … Gain, R = 0.77 Loss, R = 0.46 α = 0.86 α = 0.34 … -1.5 0 1.5 -1.5 0 1.5 -1.5 0 1.5 0 0 0 … 0.0 0.2 0.4 0.6 0.8 1.0 1.2 … 0 0.1 1 10 100 TNF Conc. ng/mL … 0 0.1 1 10 100 TNF Conc. ng/mL … Relative expresion 0.0 0.2 0.4 0.6 0.8 1.0 1.2 1.4 IL1A 1.5hrs TNF 1.5hrs … 0.125 0.25 0.5 1 2 4 8 16 32 64 … TM E M 170B V S TM 4 … O S B P L11 M A R C1 S TO M D G A T2 P LIN 1 P CK 1 H K 2 P P A R G CID E C A CA CB F A B P 4 V IM … P P P 1R 15B A D M R E P IN 1 CF H LY R M 4 CT S Z Z …