Numerical Optimization of a Microfluidic Assisted Microarray for the Detection of Biochemical Interactions

Data di pubblicazione: 12 Ott 2011

RivistaFonte dati: OPENALEXTipo OpenAlex: articleOpen Access
Autori: Emanuele Orabona, Ilaria Rea, Ivo Rendina, Luca De Stefano

Finite element method analysis was applied to the characterization of the biomolecular interactions taking place in a microfluidic assisted microarray. Numerical simulations have been used for the optimization of geometrical and physical parameters of the sensing device. Different configurations have been analyzed and general considerations have been derived. We have shown that a parallel disposition of the sensing area allows the homogeneous formation of the target molecular complex in all the active zones of the microarray. Stationary and time dependent results have also been obtained. View Full-Text

Editore
Molecular Diversity Preservation International
Fonte
Sensors
Volume
11
Fascicolo
10
Pagine
9658-9666
Citazioni
11
ID archivio
b00e697a2102357bf4936622a3a47e23
Riferimenti
Volume: 11 Issue: 10 Pages: 9658-9666