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Type: 
Journal
Description: 
Surface plasmon resonance (SPR) imaging is a promising label free method that can be used in an array format for the detection of biomolecular interactions. In this work the DNA–DNA interaction was investigated. A DNA SH-oligonucleotide sequence was immobilized onto suitable photolithography patterned gold substrates and the hybridization reaction with the complementary strand was monitored by means of changes in the optical properties of the surface. The DNA probe used in this work was specific for the 35S promoter, a marker of the presence of genetically modified organisms (GMOs).
Publisher: 
Elsevier
Publication date: 
14 Mar 2008
Authors: 

MG Manera, J Spadavecchia, A Leone, F Quaranta, R Rella, D Dell’Atti, M Minunni, M Mascini, P Siciliano

Biblio References: 
Volume: 130 Issue: 1 Pages: 82-87
Origin: 
Sensors and Actuators B: Chemical