Plastic deformation and wear of the ultra-high molecular weight polyethylene (UHMWPE) insert have been pointed out as major issues relating to the long-term stability of an orthopaedic implant. The deposition of protective hard, tough and well-adhered zirconia (ZrO2) thin films directly on the surface of the UHMWPE component via the Pulsed Plasma Deposition (PPD) technique has been already demonstrated to be a feasible way to approach this problem. In the current study, the tribo-mechanical properties of ZrO2-coated UHMWPE with respect to pristine UHMWPE were investigated in detail. Specifically, strength to local plastic deformation, indentation work portioning and creep behavior were evaluated through nanoindentation and micro-scratch tests. Further, preliminary wear data (i.e., rate and volume) were obtained by tribology tests mating coated and pristine UHMWPE with an alumina ball under dry …