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Type: 
Journal
Description: 
Human α-thrombin (TB) is a serine protease with a crucial role in coagulation and hemostasis. The monitoring of the TB level in blood serum could be of great importance in order to prevent serious damage to human health. In this work, an aptasensor is realized by in situ synthesis of a 17-mer Thrombin Binding Aptamer analogue (TBATT) on silanized macroporous silica (PSi). The interaction between TBATT and TB at different concentrations is monitored by a label-free optical method, spectroscopic reflectometry, and quantified by …
Publisher: 
Royal Society of Chemistry
Publication date: 
1 Jan 2016
Authors: 

Luca√°De Stefano

Biblio References: 
Volume: 6 Issue: 90 Pages: 86762-86769
Origin: 
RSC Advances