Neutrinoless double beta decay (0v\b {eta}\b {eta}) is considered the best potential resource to access the absolute neutrino mass scale. Moreover, if observed, it will signal that neutrinos are their own anti-particles (Majorana particles). Presently, this physics case is one of the most important research" beyond Standard Model" and might guide the way towards a Grand Unified Theory of fundamental interactions.Since the 0v\b {eta}\b {eta} decay process involves nuclei, its analysis necessarily implies nuclear structure issues. In the NURE project, supported by a Starting Grant of the European Research Council (ERC), nuclear reactions of double charge-exchange (DCE) are used as a tool to extract information on the 0v\b {eta}\b {eta} Nuclear Matrix Elements. In DCE reactions and\b {eta}\b {eta} decay indeed the initial and final nuclear states are the same and the transition operators have similar structure. Thus the measurement of the DCE absolute cross-sections can give crucial information on\b {eta}\b {eta} matrix elements. In a wider view, the NUMEN international collaboration plans a major upgrade of the INFN-LNS facilities in the next years in order to increase the experimental production of nuclei of at least two orders of magnitude, thus making feasible a systematic study of all the cases of interest as candidates for 0v\b {eta}\b {eta}.