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Type: 
Journal
Description: 
We demonstrate the realization of the first label-free optical biosensor based on the room temperature luminescence of silicon nanowires (NWs) tested for the selective detection of C-reactive protein in human serum. High aspect ratio Si NW arrays used as sensing interface, are synthesized by a fast, low cost and Si industrially compatible approach. Si NW optical biosensors are fast and offer a broad concentration dynamic range that can be tuned according to different applications. Moreover, the platform is endowed with a high selectivity toward the target analyte and a sensitivity down to the fM limit of detection, opening the route toward noninvasive analysis in biofluids such as saliva.
Publisher: 
AMER CHEMICAL SOC
Publication date: 
1 Feb 2018
Authors: 

Alessia Irrera, Antonio Alessio Leonardi, Cinzia Di Franco, Maria Jose Lo Faro, Gerardo Palazzo, Cristiano D'Andrea, Kyriaki Manoli, Giorgia Franzo, Paolo Musumeci, Barbara Fazio, Luisa Torsi, Francesco Priolo

Biblio References: 
Volume: 5 Issue: 2 Pages: 471-479
Origin: 
ACS PHOTONICS