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Using a three dimensional coupled Monte Carlo-Poisson algorithm and experimental results we studied the role of the particle-particle dipole interaction on the kinetics of a system of human cells suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. We found that the kinetics of the cells during negative/repulsive dielectrophoresis depends on the local distribution of particles. If the cells have generated long chains during positive/attractive dielectrophoresis, such chains can hinder subsequent detachment resulting in a reduction of the separation/manipulation efficiency of dielectrophoretic device. This effect can be avoided by proper design of the electrodes schema.
Publication date: 
12 Oct 2014

M Camarda, S Baldo, S Scalese, A Ballo, G Giustolisi, A Romano, F Di Raimondo, M Pucci, F Vicari, L Minafra, FP Cammarata, V Bravatà, GI Forte, G Russo, MC Gilardi, A La Magna

Biblio References: 
Pages: 58-61
2014 IEEE 9th Nanotechnology Materials and Devices Conference (NMDC)