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In this work we investigate the use of graphene as transducer in a novel biosensor for biomedical uses, in which electroactive membrane proteins would serve as biological recognition elements. Membrane proteins maintain their functionalities only if embedded in the cell membrane, so it is necessary to develop a system, which mimics their native environment. This study is focused on surface treatments of graphene to improve its biocompatibility and a first investigation of its interaction with liposomes, which rupture and spread to form a Supported Lipid Bilayer under specific surface conditions. The first step involved the characterization of the graphene membranes synthesized by Chemical Vapor Deposition, using several techniques to determine their morphological and structural properties. From these investigations, the CVD-synthesized graphene resulted to be mono- to few-layer. Next, the interaction of …
Publication date: 
27 Jul 2015

Martina Pittori, Maria Gabriella Santonicola, Luca Ortolani, Denis Gentili, Vittorio Morandi, Rita Rizzoli

Biblio References: 
Pages: 850-853
2015 IEEE 15th International Conference on Nanotechnology (IEEE-NANO)