In our work we investigate the development of a novel electrochemical biosensor that integrates a graphene layer as the transducer element for the analysis of electroactive membrane proteins. Graphene is used as transducer because of its unique properties (high surface area, electrical conductivity, ultra-high electron mobility, wide electrochemical potential window, low charge-transfer resistance, reduction of overvoltage), all of which are responsible for the enhancement of the direct electron transfer between graphene and …