Poly(dimethylsiloxane) (PDMS) is widely used in integrated microfluidics and biomedical platforms due to its many advantageous properties. However, the use of common organic solvents in synthesis and diagnostic protocols performed in PDMS-based devices has prompted the search for treatments of PDMS able to avoid the undesirable consequences of the PDMS swelling. Due to the solvent volatility, systematic underestimation of the weight-gain can result from standard measurements of swollen weight in open environment and affected by time-delay comparable to the solvent evaporation rate. In this study, we consider dichloromethane (DCM) as an example-solvent that swells PDMS and consider: i) an experimental procedure properly designed for measuring the swollen weight of PDMS with control on the weight loss due to the solvent volatility, and ii) post-curing thermal aging of PDMS for effectively …