Clin Microbiol Infect 2011; 17: 247–250AbstractEighty‐one patients affected by the novel influenza A (H1N1), hospitalized in North‐western Italy, were studied. The median age was 32 years (range 1–81 years). Fifty‐six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death.