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Postmenopausal women show the highest incidence of breast cancer in the female population and are often affected by metabolic syndrome. Metabolic syndrome (MS) - characterized by central adiposity, insulin resistance, low serum high-density lipoprotein cholesterol (HDL-C), high serum triglyceride and high blood pressure - seems to be strictly correlated to breast carcinogenesis. We enrolled 777 healthy women and women with breast cancer in our nested case-control study to evaluate the association between MS and breast cancer, analyzing anthropometric parameters (weight, height, BMI, waist and hip circumference), blood pressure, serum HDL-C, triglyceride, fasting plasma glucose, insulin, testosterone and uric acid levels and administering a questionnaire about physical activity, food intake, tobacco use, alcohol abuse, personal and familial history of disease. We found an higher prevalence of …
Taylor & Francis
Publication date: 
15 Dec 2010

Immacolata Capasso, Emanuela Esposito, Francesca Pentimalli, Anna Crispo, Maurizio Montella, Maria Grimaldi, Maria Rosaria De Marco, Ernestina Cavalcanti, Massimiliano D’Aiuto, Alfredo Fucito, Giuseppe Frasci, Nicola Maurea, Giuseppe Esposito, Tonino Pedicini, Aldo Vecchione, Giuseppe D’Aiuto, Antonio Giordano

Biblio References: 
Volume: 10 Issue: 12 Pages: 1240-1243
Cancer biology & therapy