ObjectiveWe started up an intensive program of clinical–instrumental surveillance according to Gail's model. The aim was to increase cases of early diagnosis in women at higher risk.MethodsFor 568 patients, Gail's model risk was evaluated and clinical examination, mammography, and ultrasonography were performed.ResultsAccording to Gail's model parameters among 568 patients: the mean age of menarche was 12.5 years; according to family history for breast cancer, 43%(244 patients) had a first-degree relative, 24%(136 patients) had a second-degree relative, and 33%(188 patients) had no family history; classes of age most represented were 41 to 50 years (30%) and 51 to 60 years (27%); the mean age of first live birth was 25 years; and according to number of biopsies, 326 patients had previous breast biopsies–29 patients (9%) positive for atypical hyperplasia and 297 patients (91%) positive for …