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Type: 
Journal
Description: 
In this communication, we present the fabrication and characterization of oxidized porous silicon (PSI) micropattems, obtained by direct laser writing, and chemically functionalized for biological applications. The laser local oxidation technique is a good atternative to the traditional photolithographic process since this approach allows the development of micropatterned biosensors. In fact, from a technological point of view, the standard masking of PSi by means of photoresist presents remarkable difficulties because of the low resistance to the electrochemical process. The micropatterned PSi oxidized surfaces can be properly functionalized by a specific chemical linker. The modified surface is able to link the carboxylic or aminic groups of biological probes. The binding between the functionalized surface and the biological matter has been tested by directly spotting on the PSi local oxide a fluorescent labelled antibody. The device has been characterized by FT-IR measurements and fluorescence macroscopy.
Publisher: 
World Scientific
Publication date: 
24 Jul 2008
Authors: 

G DELLA CORTE, I RENDINA

Biblio References: 
Pages: 382
Origin: 
Proceedings of the 12th Italian Conference, Sensors and Microsystems, Napoli, Italy, 12-14 February 2007