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Type: 
Journal
Description: 
This open science paper introduces a large, curated, and publicly available resource for adverse drug event (ADE) research: it includes an ADE dataset with the source code and documentation to be used by the research community. This resource (AEOLUS) derives from the publicly available US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) dataset, covering spontaneous reports of adverse drug events since 2012. The resource also integrates a legacy dataset covering 2004-2012. The final dataset results from a pipeline consolidating all relevant data for ADE research, normalizing different term usage, de-duplicating cases, mapping drugs to RxNorm, mapping drug indications and reactions to MedDRA, and generating drug-outcome pairs with associated statistics. The provided documentation and code is expected to support the evolution of this resource when updates of the …
Publisher: 
Publication date: 
1 Jan 2016
Authors: 

S Sarntivijai, D Vasant, S Jupp, G Saunders, AP Bento, D Gonzalez, J Betts, S Hasan, G Koscielny, I Dunham, H Parkinson, J Malone

Biblio References: 
Volume: 60 Pages: 23-37
Origin: 
Inform