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Type: 
Journal
Description: 
Magnetic nanorobots offer wireless navigation capability in hard‐to‐reach areas of the human body for targeted therapy and diagnosis. Though in vivo imaging is required for guidance of the magnetic nanorobots toward the target areas, most of the imaging techniques are inadequate to reveal the potential locomotion routes. This work proposes the use of radiopaque magnetic nanorobots along with microcomputed tomography (microCT) for localized in vivo imaging applications. The nanorobots consist of a contrast agent, barium sulfate (BaSO4), magnetized by the decoration of magnetite (Fe3O4) particles. The magnetic features lead to actuation under rotating magnetic fields and enable precise navigation in a microfluidic channel used to simulate confined spaces of the body. In this channel, the intrinsic radiopacity of the nanorobots also provides the possibility to reveal the internal structures by X‐ray contrast …
Publisher: 
Publication date: 
1 Mar 2023
Authors: 

Cagatay M Oral, Martina Ussia, Mario Urso, Jiri Salat, Adam Novobilsky, Michal Stefanik, Daniel Ruzek, Martin Pumera

Biblio References: 
Volume: 12 Issue: 8 Pages: 2202682
Origin: 
Advanced Healthcare Materials